Warren Workshop VI 2016

Program

6^th Charles Warren Workshop 2016
Theme of the Workshop: Finding meaning in the ambiguity of glycan structures

[DATE]
August 24 - 26, 2016
[PLACE]
Frontier Research in Applied Sciences Building
Graduate School and School of Engineering
Hokkaido University
Kita 13, Nishi 8, Kita-ku, Sapporo, Hokkaido 060-8628, Japan

Posters and Hands-On Presentations

Wednesday August 24, 2016

09:00 – 09:30 Registration

Welcome and Workshop Aims
09:30 – 09:40 Welcome
Hisashi Narimatsu
09:40 – 09:50 History of the Warren Workshop
Vernon Reinhold
09:50 – 10:00 Introduction to the Aims of the Meeting
Kiyoko F. Aoki-Kinoshita

Session 1: Glycobiology
Chair: Jianxin Gu, Hisashi Narimatsu
10:00 – 10:25 "Eliminating Ambiguity in Glycan Sequencing by
MSⁿ Disassembly"
Vernon Reinhold
10:25 – 10:50 "Nutrient Regulation of Signaling & Transcription
by O-GlcNAcylation"
Gerald Hart
10:50 – 11:15 "HIV glycosylation"
James Paulson
11:15 – 11:25 Lightning Talk 1
11:25 – 11:40 Coffee Break
11:40 – 12:05 "Total cellular glycome analysis: Method
development and its application to biological
samples"
Jun-ichi Furukawa
12:05 – 12:30 "Distribution of IgG galactosylation as a promising
biomarker for cancer screening"
Shifang Ren
12:30 – 12:55 "Multilectin assay for glycobiomarker
development"
Atsushi Kuno
12:55 – 14:00 Lunch
14:00 – 16:00 Poster Session (Odd numbers)

Session 2: Analytics
Chair: Kshitij Khatri, Nicolle Packer
16:00 – 16:25 "Rapid throughput glycomic in analysis of human
milk glycoconjugates"
Carlito Lebrilla
16:25 – 16:50 "The necessity of focused clarity amidst the
glycomic ambiguity"
Kay-Hooi Khoo
16:50 – 17:15 "Leveraging pluripotency to define cell-specific
features within multidimensional glycomic
analyses"
Michael Tiemeyer
17:15 - 17:30 Coffee Break
17:30 – 17:55 "Reverse glycomics: from glycan structure to
gene function"
Nicolle Packer
17:55 – 18:20 "Streamlining the O-glycomic LC-MS workflow for
clinical and biomedical applications"
Niclas Karlsson
18:20 – 18:30 Lightning Talk 2
18:30 Workshop Dinner

Thursday August 25, 2016

08:30 – 09:00 Registration

Session 3: Analytics
Chair: Michael Tiemeyer, Kay-Hooi Khoo
09:00 – 09:25 "A split-apply-combine approach towards
deconvolving the glycoproteome"
Kshitij Khatri
09:25 – 09:50 "xCGE-LIF: A powerful Tool in the Glycoanalytical
Toolbox"
Erdmann Rapp
09:50 – 10:15 "Glycoproteomic studies of Viral, Bacterial and
Parasitic glycosylation"
Simon North
10:15 – 10:40 "Accurate mass-based large-scale analysis of
glycosylation site-specific glycan
heterogeneity of complex protein mixture"
Hiroyuki Kaji
10:40 - 10:50 Lightning Talk 3
10:50 – 11:05 Coffee Break
11:05 – 11:30 "Designer arrays for the pinpointing, isolation and
structural assignments of natural glycan ligands
of biological and medical importance"
Ten Feizi
11:30 – 11:55 "Predicting N-glycan processing based on
enzyme-glycan accessibility"
Robert Woods
11:55 – 12:20 "Understanding glycan dynamics and interaction
by NMR and X-ray crystallography"
Yoshiki Yamaguchi
12:20 – 12:30 Lightning Talk 4
12:30 – 13:30 Lunch

Session 4: Bioinformatics
Chair: Robert Woods, Yoshiki Yamaguchi
13:30 – 13:55 "Glycologue: a new modeling framework for
O-linked glycosylation"
Gavin Davey
13:55 – 14:20 "Introducing IgCarbKB, a human immunoglobulin
glyco-atlas"
Matthew Campbell
14:20 – 14:45 "Glycomics@ExPASy: Bridging the gap"
Frederique Lisacek
14:45 – 14:55 Lightning Talk 5
14:55 – 15:10 Coffee Break
15:10 – 15:35 "Semantic Web Technologies for Integrating
Glycan-related Databases"
Kiyoko F. Aoki-Kinoshita
15:35 – 16:00 "GRITS Toolbox – An extendible software
platform for the processing and archiving
of glycomics data"
Rene Ranzinger
16:00 – 16:10 Lightning Talk 6
16:10 – 16:25 "MIRAGE Working Group Report"
Carsten Kettner
16:30 – 18:30 Poster (Even numbers) and Bioinformatics
Hands-on Session
Sapporo Beer Garden on your own.
Please email organizers if you plan on going by July 15 as space is limited and reservations are required.

Friday August 26, 2016

09:00 – 09:30 Registration

Session 5: Glycobiology/Computational Glycobiology
Chair: James Paulson, Tadashi Suzuki
09:30 – 09:55 "Shaping Glycans by DNA Scissors and Turning
Glycosciences Into Lego Toying"
Henrik Clausen
09:55 – 10:20 "Whether the tumor suppressor p53 has a novel
glycosyl-modification"
Yan Zhang
10:20 – 10:45 "Roles of N-glycan in epithelial-mesenchymal
transition (EMT) and cellular signaling"
Jianguo Gu
10:45 – 11:00 Coffee Break
11:00 – 11:25 "Identification of a post-translational modification
with ribitol-phosphate and its defect in muscular
dystrophy"
Tatsushi Toda
11:25 – 11:50 "Can basic science contribute to cure a human
genetic disorder?"
Tadashi Suzuki
11:50 – 13:00 Lunch

Discussion
Chair: Kiyoko F. Aoki-Kinoshita
13:00 – 14:30 Open Discussion
14:30 – 14:45 Coffee Break
14:45 – 15:30 Open Discussion
15:30 – 16:00 Discussion for 7th Warren Workshop in 2018
16:00 Meeting Adjournment